Cell-penetratingpeptide相关论文
Chemoresistance is a major barrier against effective treatment outcomes in cancer.MDR cancer cells can survive through c......
Dual-mode Targeting and Penetrating Strategy for Cancer-associated Fibroblast Based Tumor Therapy vi
Although many multifunctional drug-loaded nanomaterials have been designed to increase drug delivery into tumor cells,on......
Albumin Nanoparticles for Biomimetic Drug Delivery via Albumin-Binding Protein Pathways for Antiglio
Nutrient transporters have been explored for biomimetic delivery targeting the brain.The albumin-binding proteins(e.g.,S......
Inhibition of HBV cccDNA transcription by CPP-PNA conjugates assembled on an oligonucleotide scaffol
Objectives: Current treatment options for chronic hepatitis B depend on interferon α or nucleos(t)ide analogs,which eff......
Synthesis, in vitro and in vivo evaluation of dual-functional tLyP-1 conjugated hyaluronic acid-pacl
Paclitaxel (PTX) is an antitumor drug which has been widely adopted in clinical treatment of cancer for years.However, i......
During the last decade, cell-penetrating peptides (CPPs) have been extensively employed to deliver drugs into cells due ......
Intein-mediated site-specific synthesis of activatableprotein delivery system:turning PEG dilemma in
Clinical translation of protein toxins for cancer therapy is restrained by the short half-life and poor cellular uptake ......
Monomeric insulin and low molecular weight protamine chemical chimera for enhanced insulin intestina
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In recent years,cell-penetrating peptides (CPPs) have been proven to be a useful tool in improving the membrane transloc......
The backbone stereochemistry influences the intracellular distribution and uptake mechanism of oligo
D-arginine oligomers have been widely used as intracellular delivery vectors both in in vitro and in vivo application. N......
目的研究自噬诱导肽Beclin 1及其经穿膜肽TAT修饰后所得TAT-Beclin 1对乳腺癌的体外自噬诱导作用及体内外疗效。方法采用透射电子......